Somatropin Preparation & Injection Instructions
IMPORTANT: Information provided on this site is intended only for patients who have received their medications from Palm Beach Preventive Medicine, Inc.™  If you are not a Palm Beach Preventive Medicine, Inc.™ patient, please consult your own doctor or pharmacist for instructions and guidance. Instructions are provided for informational and educational purposes only, and are not intended to substitute for medical advice.
Before preparation, wash your hands, and be sure you have everything you need.
Remove the protective caps from the two vials. With one alcohol swab, clean both the rubber top of the vial that contains the powder and the rubber top of the vial that contains Bacteriostatic Water.
Use next the sterile Bacteriostatic Water vial, the disposable 3mL syringe and an 18-guage needle.
Attach the needle to the syringe (if not attached already). Pull back the syringe plunger and fill the syringe with air. Push the needle fitted to the syringe through the rubber top of the Bacteriostatic Water vial, push all the air from the syringe into the vial, turn the vial upside down, and withdraw the Bacteriostatic Water (1.8mL for a 6mg vial, 2.7mL for a 9mg vial) from the vial into the syringe. Remove the syringe and needle from the vial.
Next take the syringe with the Bacteriostatic Water in it and push the needle through the rubber stopper of the vial that contains the Somatropin (white powder.) Inject the Bacteriostatic Water slowly. Aim the stream of liquid against the glass wall in order to avoid foam. Remove the syringe and needle and dispose of them.
Gently swirl the vial until the content is completely dissolved. Do not shake.

If the medicine is cloudy or contains particles, it should not be used. The medicine must be clear and colorless after mixing.

Store the vial in a refrigerator at 36° to 46° F (2° to 8° C) after mixing and after each use.

Measuring the Dose to Be Injected:
Next use the sterile, disposable 1mL (or similar) syringe and needle for subcutaneous injection.

Push the needle through the rubber top of the vial that contains the Somatropin that you have just mixed.

Turn the vial and the syringe upside down.

Be sure the tip of the syringe is in the mixed medicine.

Pull back on the plunger slowly and withdraw the dose prescribed by your doctor into the syringe.

Hold the syringe with the needle in the vial pointing up and remove the syringe from the vial.

Check for air bubbles in the syringe. If you see any bubbles, pull the plunger slightly back; tap the syringe gently, with the needle pointing upwards, until the bubble disappears. Push the plunger slowly back up to the correct dose. If there is not enough medicine in the syringe after removing the air bubbles, draw more medicine into the syringe from the mixed medicine vial and repeat checking for bubbles.

Look at the mixed medicine in the syringe before using. Do not use if discolored or particles are present. You are now ready to inject the dose.


Choose the site of injection on your body. The best sites for injection are tissues with a layer of fat between skin and muscle such as the upper leg (thigh), buttocks, or stomach area (abdomen). Do not inject near your belly button (navel) or waistline.

Make sure you rotate the injection sites on your body. Inject at least ½ inch from the last injection. Change the places on your body where you inject.

Before you make an injection, clean your skin well with an alcohol swab. Wait for the area to air dry.

With one hand, pinch a fold of loose skin at the injection site. With your other hand, hold the syringe as you would a pencil. Insert the needle into the pinched skin straight in or at a slight angle (an angle of 45° to 90°).
After the needle is in, remove the hand used to pinch the skin and use it to hold the syringe barrel. Pull back the plunger very slightly with one hand. If blood comes into the syringe, the needle has entered a blood vessel. Do not inject into this site; withdraw the needle and repeat the procedure at a different site. If no blood comes into the syringe, inject the solution by pushing the plunger all the way down gently.
Pull the needle straight out of the skin. After injection, press the injection site with a small bandage or sterile gauze if needed for bleeding, for several seconds. Do not massage or rub the injection site.
After Injecting:

Discard the injection materials.

Dispose the syringes safely in a closed container. You can ask your healthcare provider or pharmacist for a "sharps" container. A sharps container is a special container to put used needles and syringes in. You can return a full sharps container to your pharmacist or healthcare provider for disposal.

The vial of mixed medicine must be stored in the refrigerator in its carton at 36° to 46° F (2° to 8° C). DO NOT FREEZE.
The solution should be clear after removal from the refrigerator. If the solution is cloudy or contains particles, discard the vial. Do not inject the medicine from this vial. Start over with a new vial.
Before each use disinfect the rubber top of the reconstituted vial with an alcohol swab. You MUST use a new disposable 1mL syringe and needle for each injection.
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8409 N. Military Trail, Suite 126 | Palm Beach Gardens, FL 33410
Phone: 561.296.9200 Fax: 561.296.9215